Comparison of 5 × 5 Gy and 10 × 3 Gy for metastatic spinal cord compression using data from three prospective trials
نویسندگان
چکیده
منابع مشابه
1x8 Gy versus 5x4 Gy for metastatic epidural spinal cord compression: a matched-pair study of three prognostic patient subgroups
BACKGROUND This study provides separate comparisons of 1 × 8 Gy to 5 × 4 Gy for metastatic epidural spinal cord compression (MESCC) in patients with poor, intermediate and favorable survival prognoses. METHODS Patients receiving 1 × 8 Gy were matched to patients receiving 5 × 4 Gy for age, gender, performance status, tumor type, involved vertebrae, other bone metastases, visceral metastases, ...
متن کاملA matched-pair analysis comparing 5x4 Gy and 10x3 Gy for metastatic spinal cord compression (MSCC) in patients with favorable survival prognoses
BACKGROUND It is currently not possible to get an approval of our ethics committee for a randomized trial cmparing 5x4 Gy and 10x3 Gy for MSCC that includes patients with favorable survival prognoses. Therefore, this matched-pair study following strict matching criteria was perfomed instead. METHODS In this study, 142 receiving 5x4 Gy were retrospectively matched (1:1) to 142 patients receivi...
متن کاملMetastatic Spinal Cord Compression
According to recent Canadian statistics, an estimated 186,400 new cases of cancer and 75,700 deaths from cancer are expected in Canada in 20121. In general, between 40% and 70% of patients with advanced solid tumours such as those of breast, prostate, and lung will develop bone metastases2. The spine is the most common site for bone metastasis, affecting up to 30% of cancer patients3. Overall, ...
متن کاملProspective randomised multicenter trial on single fraction radiotherapy (8 Gy x 1) versus multiple fractions (3 Gy x 10) in the treatment of painful bone metastases.
BACKGROUND AND PURPOSE To investigate whether single-fraction radiotherapy is equal to multiple fractions in the treatment of painful metastases. PATIENTS AND METHODS The study planned to recruit 1000 patients with painful bone metastases from four Norwegian and six Swedish hospitals. Patients were randomized to single-fraction (8 Gy x 1) or multiple-fraction (3 Gy x 10) radiotherapy. The pri...
متن کاملMetastatic spinal cord compression: diagnosis and management.
Between five and 10 in every 200 patients with terminal cancer will have metastatic spinal cord compression (MSCC) within their last two years of life. It is an oncological emergency. 2 MSCC is caused by compression of the dural sac and its contents (spinal cord or cauda equina) by an extradural or intradural mass, and it leads to irreversible neurological damage such as paraplegia or tetrapleg...
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ژورنال
عنوان ژورنال: Radiation Oncology
سال: 2021
ISSN: 1748-717X
DOI: 10.1186/s13014-020-01737-7